Personally I've no doubt we'll be seeing more games from this series though. It might - or might not - be the end of humanity's war with the Locust Horde but there are plenty more tales to tell in the Gears saga. Such as the earlier Pendulum Wars, and the events surrounding E-Day.
But 'nuff with speculation. Take a looksee at "Ashes to Ashes", the first trailer for Gears of War 3!
The song is "Heron Blue" by folk rock group Sun Kil Moon. Now you know. And knowing is half the battle.